A Korean scientist solved the secret of human
chromosome number 19.
It has been found out that an experiment developed
by a Korean scientist made a large contribution
in decoding chromosome number 19 wherein genes
related to incurable human diseases such as diabetes,
Alzheimer's disease, etc. are concentrated.
On April 8, 2004, Busan Dong-A University stated
that Professor Lim Sun-Hee (41)'s team at the
School of Biological Science, College of Natural
Sciences participated as a joint author of a paper,
"Examination on the DNA sequence of human
chromosome number 19' published in the April 1,
2004 edition of a science expert paper, 'Nature',
and that the experiment developed by the team
played a decisive role in completing the decoding.
The chromosome decoding work (Human Genome Project)
is a project examining 3 billion DNA sequences
of the human gene containing the secret of human
living, aging, diseases, and dying. Even though
it has been reported as if the Human Genome Project
has already been completed, 1% of the DNA sequence
was still unknown.
Until now, scientists examined DNA sequences
by amplifying the human gene fragments in coliform
bacillus. However, unlike human (eucaryote), since
coliform bacillus is a prokaryote whose nucleus
is not enclosed in a membrane, 1% has not been
completed by forming an unstable environment for
example by removing a part of a human gene fragment.
Professor Lim's team found out this 1% of DNA
sequence by the method for amplifying gene fragments
using yeast, a eucaryote instead of using coliform
bacillus (TAR). This method has been introduced
in the February edition of 'Genome Research'.
Professor Lim said, "there were four empty
cracks in the chromosome number 19. After filling
them up, four new genes were discovered, unexpectedly.
One of them was the SCK1 gene which controls human
faculty of speech. It can also be used as a target
for confirming one's own child."
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